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Methadone Binds to opiate receptors in the CNS. Buy Methadone Online without prescription. Alters the perception of and response to painful stimuli while producing generalized CNS depression. Therapeutic Effects: Decrease in the severity of pain. Suppression of withdrawal symptoms during detoxification and maintenance from heroin and other opioids.
1. For the treatment of moderate to severe pain not responsive to non-narcotic analgesics.
2. For detoxification treatment of opioid addiction (heroin or other morphine-like drugs).
3. For maintenance treatment of opioid addiction (heroin or other morphine-like drugs), in conjunction with appropriate social and medical services. Acute Pain – Maintenance patients on a stable dose of methadone who experience physical trauma, postoperative pain or other acute pain cannot be expected to derive analgesia from their existing dose of methadone. Such patients should be administered analgesics, including opioids, in doses that would otherwise be indicated for non-methadone-treated patients with similar painful conditions. Due to the opioid tolerance induced by methadone, when opioids are required for management of acute pain in methadone patients, somewhat higher and/or more frequent doses will often be required than would be the case for non-tolerant patients.
Methadone is contraindicated in patients with a known hypersensitivity to methadone hydrochloride or any other ingredient. Methadone is contraindicated in any situation where opioids are contraindicated such as patients with respiratory depression (in the absence of resuscitative equipment or in unmonitored settings), and in patients with acute bronchial asthma or hypercarbia. Methadone is contraindicated in any patient who has or is suspected of having paralytic ileus. Methadone should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Pediatric Use Safety and effectiveness in pediatric patients below the age of 18 years have not been established. The major hazards of methadone are respiratory depression and, to a lesser degree, systemic hypotension. Buy Methadone Online without Prescription.
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